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Not to be confused with the related chemical naloxone. Naltrexone reverses the effects of opioids and is used primarily in the management of alcohol dependence and opioid dependence. It is marketed in generic form as its hydrochloride salt, naltrexone hydrochloride, and marketed under the trade names Revia and Depade.
Naltrexone can help keep you from feeling a "need" to use the opioid. Vivitrol injection is also used to treat alcoholism by reducing your urge to drink alcohol. This may help you drink less or stop drinking altogether. Naltrexone will not decrease the effects of alcohol you recently consumed.
Taking large amounts of this drug can induce naltrexone overdose symptoms. Do not take narcotic painkillers or drink alcohol while you are using naltrexone, as doing so can cause adverse side effects, including opioid overdose or alcohol poisoning.
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In terms of dosing, 50mg of naltrexone have the ability to block the effects of opioids for about 24 hours. Clinical studies suggest that doubling the dose will block opioid effects for 48 hours, while 150mg of naltrexone can provide blockage for approximately 72 hours.
Concentrations of naltrexone begin to slowly decline about 2 weeks after dosing, and levels of the medication stay measurable for a month or more. The elimination half life of naltrexone from Vivitrol ranges between 5 to 10 days.
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