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Is PBC life threatening? The immune system may reject a donated liver, which could be life threatening. It's now common for people to still be healthy and well more than 20 years after a liver transplant. There's a risk of PBC developing in your new liver, but this isn't usually a major concern because it often takes a long time to develop.
How serious is PBC? The fatigue in PBC is not linked to the severity of the liver disease. Patients can have early disease but still have profound fatigue, while others with more advanced disease may have no fatigue at all. Portal hypertension usually occurs after a patient develops cirrhosis.
Can PBC affect your eyes? Advanced PBC. Medication can usually help to delay liver damage in people with PBC, but as the liver slowly becomes more scarred and damaged (eventually ending up with cirrhosis), you may have additional symptoms. These can include: yellowing of the skin and whites of the eyes (jaundice)
Can you die suddenly from cirrhosis of the liver? Without a liver transplant, kidney failure usually is fatal, often causing several organs throughout the body to fail. Cancer: People often develop liver cancer before they develop cirrhosis. You may die within 3-6 months after diagnosis if the cancer remains untreated.
What causes itching with PBC? In cholestasis, therefore, the bile acids back up from the liver, accumulate in the blood, and, for some years, were presumed to be the cause of the itching. Modern studies, however, have just about refuted the notion that the itching in PBC and other cholestatic liver diseases is caused by bile acids.
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